A clinical trial shows that the effects of high-frequency rTMS are superior to those of low-frequency rTMS in reducing Parkinson’s disease symptoms.
The treatment is more effective in patients with akinetic psychiatrist near me-rigid Parkinson’s, those with slow movements and rigidity, than in patients with the tremor-dominant form of the disease.
The Journal of Parkinson’s Disease published a study on the effects of 20 and 1 Hz repetitive magnetic stimulation on Parkinson’s disease.
Non-invasive therapies that help the brain and treat the symptoms of Parkinson’s disease are an alternative to pharmacologic treatments. rtms uses currents to help the brain. This approach has been shown to help Parkinson’s patients.
The therapy can be administered at different frequencies, which can have different effects. It is not clear which frequencies yield better results.
The researchers at Egypt’s Assiut University conducted a clinical trial to see if rTMS could help Parkinson’s patients.
The patients were assigned to one of the groups. The groups received a total of 2,000 pulse every day for 10 days, either at a 20 or 1 Hz rate.
The researchers measured the motor symptoms using the Unified Parkinson’s Disease Rating Scale part III (UPDRS) and looked for differences before and after the last session and the end of the treatment as a primary outcome.
The secondary outcomes included changes in the Instrumental Activity of Daily Living.
The treatment improved the scores of both groups, but the effects were slightly better in the high-frequency group. High-frequency patients showed better scores than low-frequency patients after one month.
The immediate effects of both 1 and 20 Hz rTMS were similar, but the effect was only maintained after a month.
They said that 20Hz rTMS increased excitability as measured by the larger response to single TMS pulse, while there was a tendency for excitability to be reduced after 1Hz rTMS.
The researchers performed an exploratory analysis to see if the therapy was more effective in patients with Parkinson’s disease.
The data suggested that akinetic-rigid patients benefit from 20 Hz treatment, while there was no effect on the tremor-dominant form. The investigators stated that treatment with 1 Hz rTS had no effect on either group.
They concluded that 20 Hz rTMS over the primary motor cortex may be better for patients with akinetic-rigid symptoms. Studies with a lot of people should be able to confirm the results.